Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: KIRTLKNNM FSKFKKLKSL DLQQNEISKI ESEAFFGLNK LTTLLLQHNQ IKVLTEEVFI YTPLLSYLRL YDNPWHCTCE IETLISMLQI PRNRNLGNYA KCESPQEQKN KKLRQIKSEQ LCNEEEKEQL DPKPQVSGRP PVIKPEVDST FCHNYVFPIQ TLDCKRKELK KVPNNIPPDI VKLDLSYNKI NQLRPKEFED VHELKKLNLS SNGIEFIDPA AFLGLTHLEE LDLSNNSLQN FDYGVLEDLY FLKLLWLRDN PWRCDYNIHY LYYWLKHHYN VHFNGLECKT PEEYKGWSVG KYIRSYYEEC PKDKLPAYPE SFDQDTEDDE WEKKHRDHTA KKQSVIITIV G (92-441 aa encoded by BC027903)
Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 37 kDa leucine-rich repeat (LRR) protein; leucine-rich repeat (LRR) protein; Leucine-rich repeat-containing protein 17; p37NB
Gene Aliases: 37kDa; 4833425M04Rik; 6130400C22Rik; LRRC17; P37NB; UNQ3076/PRO9909
UniProt ID: (Human) Q8N6Y2, (Mouse) Q9CXD9
Entrez Gene ID: (Human) 10234, (Mouse) 74511
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