Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MRQSGASQP LLINMYLPDP VGDGLFKDGK NPSWGPLSPA VQKGSGQIQL WQFLLELLAD RANAGCIAWE GGHGEFKLTD PDEVARRWGE RKSKPNMNYD KLSRALRYYY DKNIMSKVHG KRYAYRFDFQ GLAQACQPPP AHAHAAAAAA AAAAAAQDGA LYKLPAGLAP LPFPGLSKLN LMAASAGVAP AGFSYWPGPG PAATAAAATA ALYPSPSLQP PPGPFGAVAA ASHLGGHYH (1-238 aa encoded by BC023511 )
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ETS-domain transcription factor Pet-1; FEV (ETS oncogene family); FEV (fifth Ewing variant); Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; pheochromocytoma 12 ETS (E26 transformation-specific); Protein FEV
Gene Aliases: FEV; HSRNAFEV; mPet-1; PET-1; PET1
UniProt ID: (Human) Q99581, (Mouse) Q8QZW2
Entrez Gene ID: (Human) 54738, (Mouse) 260298
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support