Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: SILSTEDPN QLTVNSLNSD ATVNTDFGDE FYSAFIAEPS ISNSMPSPAT LSHSLSELLN GPIDVSDLSL CKAFNQNHPE STAEFNDSDS GISLNTSPSV ASPEHSVESS SYGDTLLGLS DSEVEELDSA PGSVKQNGPK TPVHSSGDMV QPLSPSQGQS THVHDAQCEN TPEKELPVSP GHRKTPFTKD KHSSRLEAHL TRDELRAKAL HIPFPVEKII NLPVVDFNEM MSKEQFNEAQ LALIRDIRRR GKNKVAAQNC RKRKLENIVE LEQDLDHLKD EKEKLLKEKG ENDKSLHLLK KQLSTLYLEV FSMLRDEDGK PYSPSEYSLQ QTRDGNVFLV PKSKKPDVKK N (256-605 aa encoded by BC011558)
Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.
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