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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:100-1:500 | - |
Immunocytochemistry (ICC/IF) |
2-4 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rat / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1B2D8 |
Immunogen |
This antibody was raised against peptide comprising amino acids 1-39 of mouse AATF (Apoptosis-antagonizing transcription factor) (NP_062790). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.5, with 30% glycerol |
Contains |
0.035% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2793767 |
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis-antagonizing transcription factor; Protein AATF; Rb-binding protein Che-1; Traube protein
Gene Aliases: 4933415H02Rik; 5830465M17Rik; AATF; BFR2; CHE-1; CHE1; DED; HSPC277; Trb
UniProt ID: (Human) Q9NY61, (Mouse) Q9JKX4
Entrez Gene ID: (Human) 26574, (Mouse) 56321
Molecular Function:
chromatin/chromatin-binding, or -regulatory protein
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