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|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||fusion protein of human MRP6, containing amino acids 764-964|
|Storage buffer||tissue culture supernatant with 0.7% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay dependent.|
|Immunocytochemistry (ICC)||1:20 - 1:50|
|Immunohistochemistry (Paraffin, Frozen) (IHC (P, F))||1:20 - 1:50|
|Western Blot (WB)||1:20 - 1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody will not cross-react with human MDR1, MRP1, MRP2, MRP3, MRP4 or MRP5.
For immunohistochemistry (paraffin) applications, it is recommended to pretreat antibody with 0.01 M citric acid, pH 6.0, in distilled water at 100°C 3 times for 5 minutes.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
anthracycline resistance-associated protein; ATP-binding cassette sub-family C member 6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; MRP6; multi-specific organic anion transporter E
ABC34; ABCC6; ARA; EST349056; GACI2; MLP1; MOAT-E; MOATE; MRP6; PXE; PXE1; URG7