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OriGene
ACAT2 Monoclonal Antibody (OTI5F7), TrueMAB™
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
TA501219
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI5F7
Immunogen
Full length human recombinant protein of human ACAT2 produced in HEK293T cell.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetoacetyl Coenzyme A thiolase; acetyl-CoA transferase-like protein; acetyl-Coenzyme A acetyltransferase 2; acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase); acetyl-Coenzyme A acetyltransferase 3; ACTL; AE1; BND3; CD233; cytosolic acetoacetyl-CoA thiolase; DI; EMPB3; EPB3; FR; liver regeneration-related protein LRRG062; RTA1A; SW; unnamed protein product; WD; WD1; WR
Gene Aliases: Ab2-076; Acat3
UniProt ID: (Human) Q9BWD1, (Rat) Q5XI22
Entrez Gene ID: (Human) 39, (Dog) 484063, (Rat) 308100
lipid metabolic process
fatty acid metabolic process
farnesyl diphosphate biosynthetic process, mevalonate pathway
liver development
cholesterol biosynthetic process
phosphate-containing compound metabolic process
isopentenyl diphosphate biosynthetic process, mevalonate pathway
organophosphate metabolic process
cellular response to nutrient
geranylgeranyl diphosphate biosynthetic process
zymosterol biosynthetic process
ketone body catabolic process
cellular response to fatty acid
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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