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Invitrogen
AKR1B1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
AKR1B1 Antibody (PA5-84125)
Relative expression in different tissues in IHC: Detection of differential expression levels of AKR1B1 demonstrates antibody specificity. Immunohistochemical analysis of AKR1B1 using anti-AKR1B1 Polyclonal Antibody (Product #PA5-84125), shows significant staining of AKR1B1 in adrenal gland and shows minimal or weak staining in cerebral cortex tissues. The relative expression levels of AKR1B1 within each ti... View More
Product Details
PA5-84125
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human AKR1B1. Recombinant protein control fragment (Product #RP-104952).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791277
Product Specific Information
Immunogen sequence: VTPERIAENF KVFDFELSSQ DMTTLLSYNR NWRVCALLSC TSHKDY
Target Information
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Aldehyde reductase; aldehyde reductase 1; aldo-keto reductase family 1; Aldo-keto reductase family 1 member B1; aldo-keto reductase family 1, member B1 (aldose reductase); Aldose reductase; AR; Lii5-2 CTCL tumor antigen; low Km aldose reductase; member B1 (aldose reductase)
Gene Aliases: ADR; AKR1B1; ALDR1; ALR2; AR
UniProt ID: (Human) P15121
Entrez Gene ID: (Human) 231
tissue homeostasis
carbohydrate metabolic process
sorbitol biosynthetic process
C21-steroid hormone biosynthetic process
response to stress
response to water deprivation
naphthalene metabolic process
stress-activated protein kinase signaling cascade
norepinephrine metabolic process
daunorubicin metabolic process
doxorubicin metabolic process
fructose biosynthetic process
positive regulation of JAK-STAT cascade
positive regulation of smooth muscle cell proliferation
oxidation-reduction process
maternal process involved in female pregnancy
cellular response to hydrogen peroxide
inner medullary collecting duct development
response to thyroid hormone
cellular response to methylglyoxal
cellular response to peptide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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