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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 62 and 304 of Human ALAS-H|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29966 targets ALAS-H in WB applications and shows reactivity with Human samples.
The PA5-29966 immunogen is recombinant fragment corresponding to a region within amino acids 62 and 304 of Human ALAS-H.
Delta-aminolevulinate synthase (ALAS; EC 126.96.36.199) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2 (MIM 301300).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
5-aminolevulinate synthase; 5-aminolevulinic acid synthase 1; ALAS; ALAS3; ALASH; aminolevulinate, delta-, synthase 1; delta-ALA synthase 1; delta-aminolevulinate synthase 1; MIG4; migration-inducing protein 4; mitochondrial; nonspecific
ALAS; ALAS-H; ALAS1; ALAS3; ALASH; MIG4; OK/SW-cl.121