Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
ALOX5 Recombinant Rabbit Monoclonal Antibody (ARC1926)
FIGURE: 1 / 5
ALOX5 Antibody (MA5-38050) in ICC/IF
Confocal imaging (Immunocytochemistry) of ALOX5 in U-2 OS cells. Samples were incubated with ALOX5 Monoclonal antibody (Product # MA5-38050) using a dilution of 1:100 (Red). The cells were counterstained with alpha Tubulin Mouse mAb (dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
Product Details
MA5-38050
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC1926
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ALOX5 (P09917)
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897968
Product Specific Information
Positive Samples: Raji, Rat lung
Immunogen sequence: CYRWITGDVE VVLRDGRAKL ARDDQIHILK QHRRKELETR QKQYRWMEWN PGFPLSIDAK CHKDLPRDIQ FDSEKGVDFV LNYSKAMENL FINRFMHMFQ S
Target Information
This gene encodes a protein which, with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5 - Lipoxygenase; 5-lipoxygenase; 5-LO; Arachidonate 5-lipoxygenase; arachidonic 5-lipoxygenase alpha-10 isoform; arachidonic 5-lipoxygenase delta-10-13 isoform; arachidonic 5-lipoxygenase delta-13 isoform; arachidonic 5-lipoxygenase delta-p10 isoform; arachidonic acid 5-lipoxygenase; leukotriene A4 synthase; LOX-5; lox5; Polyunsaturated fatty acid 5-lipoxygenase; RP11-67C2.3
Gene Aliases: 5-LO; 5-LOX; 5LO; 5LPG; 5LX; AI850497; ALOX5; F730011J02; LOG5; LOX5A
UniProt ID: (Human) P09917, (Rat) P12527, (Mouse) Q3TB75
Entrez Gene ID: (Human) 240, (Rat) 25290, (Mouse) 11689
acute inflammatory response
leukotriene production involved in inflammatory response
leukotriene metabolic process
response to nutrient
sensory perception of pain
arachidonic acid metabolic process
leukotriene biosynthetic process
lipoxygenase pathway
positive regulation of vasoconstriction
response to hyperoxia
oxidation-reduction process
lipoxin metabolic process
inflammatory response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support