|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||synthetic peptide TDACVTPVLT FEEWHHD(C), corresponding to C Terminal amino acids 290-307 of Human AMCR, the peptide was modified post-synthesis.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunomicroscopy (IM)||Assay Dependent|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31262 detects AMCR from mouse, human samples.
PA1-31262 has been successfully used in immunohistochemistry, immunomicroscopy and Western blot applications.
The PA1-31262 immunogen is: Synthetic peptide: TDACVTPVLT FEEWHHD(C), corresponding to C Terminal amino acids 290-307 of Human AMCR, the peptide was modified post-synthesis.
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.