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This antibody is predicted to react with bovine, canine, human and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Apoptosis signal-regulating kinase 2; MGC125653; MGC20114; Mitogen-activated protein kinase kinase kinase 6; OTTHUMP00000005063
Gene Aliases: ASK2; MAP3K6; MAPKKK6; MEKK6
UniProt ID: (Human) O95382
Entrez Gene ID: (Human) 9064, (Rat) 313022
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