|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:5000-1:20,000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 1 and 103 of Human Histone H4|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-32029 targets Histone H4 (acetyl) in IHC (P) and WB applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-32029 immunogen is synthetic peptide corresponding to a region within amino acids 1 and 103 of Human Histone H4.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: germinal histone H4; H4 histone family, member A; H4 histone family, member I; H4/A; H4FA; H4K12ac; H4K16ac; H4K5ac; H4K8ac; HIST1H4A; histone 1, H4a; histone 1, H4b; histone cluster 1, H4a; histone H4; Histone H4A
Gene Aliases: H1ft; H4/I; H4FA; H4FI; Hist4; Hist4h4
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