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Invitrogen
Acrosomal Vesicle Protein Polyclonal Antibody
FIGURE: 1 / 1
Acrosomal Vesicle Protein Antibody (PA5-28485) in WB
Western Blot using Acrosomal Vesicle Protein Polyclonal Antibody (Product # PA5-28485). Sample (50 µg of whole cell lysate). Lane A: mouse testis. 12% SDS PAGE. Acrosomal Vesicle Protein Polyclonal Antibody (Product # PA5-28485) diluted at 1:10,000.
Product Details
PA5-28485
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 55 and 265 of Human Acrosomal vesicle protein
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545961
Product Specific Information
Recommended positive controls: mouse testis.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a testis-specific, differentiation antigen, acrosomal vesicle protein 1, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. This gene consists of 4 exons and its alternative splicing generates multiple distinct transcripts, which encode protein isoforms ranging from 81 to 265 amino acids. The longest transcript is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. It is suggested that phenomena of cryptic splicing and exon skipping occur within this gene. The acrosomal vesicle protein 1 may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acrosomal protein SP-10; Acrosomal vesicle protein 1; MSA-63; sperm protein 10
Gene Aliases: ACRV1; D11S4365; Msa63; SP-10; SPACA2
UniProt ID: (Human) P26436, (Mouse) P50289
Entrez Gene ID: (Human) 56, (Mouse) 11451
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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