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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 427 and 641 of Human alpha 2 Macroglobulin|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29584 targets Alpha2 Macroglobulin in WB applications and shows reactivity with Human samples.
The PA5-29584 immunogen is recombinant protein fragment corresponding to a region within amino acids 427 and 641 of Human alpha 2 Macroglobulin.
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A2MD; alpha-2-M; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5; CPAMD5; FWP007; S863-7
A2M; A2MD; CPAMD5; FWP007; S863-7