|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant, full length, human angiogenin protein.|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||1-2 µg/ml|
|Western Blot (WB)||1-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
MA1-20177 detects angiogenin in human samples.
MA1-20177 has been successfully used in ELISA and Western blot procedures.
The MA1-20177 immunogen is recombinant, full length, human angiogenin protein.
Angiogenin is a member of the ribonuclease superfamily with approximately 35% amino acid sequence identity with pancreatic RNase. Angiogenesis is the formation of blood vessels or capillaries from existing blood vessels due to specific signals. Angiogenin induces the growth of new blood vessels. Cells that express angiogenin include vascular endothelial and smooth muscle cells, fibroblasts, normal colonic epithelium, normal peripheral blood lymphocytes, lung and colonic epithelial tumor cell lines, and primary gastrointestinal adenocarcinomas. Angiogenin is also present in normal human plasma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Compartmentalized, functional role of angiogenin during spotted fever group rickettsia-induced endothelial barrier dysfunction: evidence of possible mediation by host tRNA-derived small noncoding RNAs.
MA1-20177 was used in immunocytochemistry to study the role of angiogenin in endothelial barrier dysfunction in spotted fever group rickettsia
|Gong B,Lee YS,Lee I,Shelite TR,Kunkeaw N,Xu G,Lee K,Jeon SH,Johnson BH,Chang Q,Ha T,Mendell NL,Cheng X,Bouyer DH,Boor PJ,Ksiazek TG,Walker DH||BMC infectious diseases (13:null)||2013|