Immunogen sequence: MSTVHEILCK LSLEGDHSTP RLKDDIKSIM DNFTEIIKTA KIEDETQVSR ATQGEQDNYE MHVRAANIVR AGESLMKLVS DLKQFLILND FPSVNEAIDQ RNQQLRTLQE ECDRKLITLR DEISIDLYEL EEEYYSSRYK; Positive Samples: SH-SY5Y, HepG2, Mouse lung; Cellular Location: Melanosome, basement membrane, extra; Cellular matrix, extra; Cellular space
This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 33-kDa calcimedin; 33-kDa lymphocyte Ca<2+>- binding protein; 33kDa lymphocyte Ca<2+>- binding protein; 36-kDa calelectrin; Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; calpactin I heavy polypeptide; Calpactin-1 heavy chain; chromobindin 8; Chromobindin-8; epididymis secretory protein Li 270; Lipocortin II; p36; PAP-IV; Placental anticoagulant protein IV; Protein I
Gene Aliases: ANX2; ANX2L4; ANXA2; AW215814; CAL1H; HEL-S-270; LIP2; LPC2; LPC2D; P36; PAP-IV