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|Tested species reactivity||Mouse, Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of ApoO expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunoprecipitation (IP)||See 1 publications below|
MA5-15493 targets ApoO in IHC and WB applications and shows reactivity with Human and mouse samples.
The MA5-15493 immunogen is purified recombinant fragment of ApoO expressed in E. Coli.
MA5-15493 detects ApoO which has a predicted molecular weight of approximately 22.2kDa.
This gene is a member of the apolipoprotein family. Members of this protein family are involved in the transport and metabolism of lipids. The encoded protein associates with HDL, LDL and VLDL lipoproteins and is characterized by chondroitin-sulfate glycosylation. This protein may be involved in preventing lipid accumulation in the myocardium in obese and diabetic patients. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 3, 4, 5, 12 and 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The non-glycosylated isoform of MIC26 is a constituent of the mammalian MICOS complex and promotes formation of crista junctions.
MA5-15493 was used in immunoprecipitation and western blot to study the functional role of MIC26 in mitochondria
|Koob S,Barrera M,Anand R,Reichert AS||Biochimica et biophysica acta (1853:1551)||2015|
apolipoprotein O; APOO; brain my025; FAM121B; family with sequence similarity 121B; MGC4825; MICOS complex subunit MIC23; MYO25
0610008C08Rik; 1110019O03Rik; APOO; FAM121B; MIC23; MIC26; My025; UNQ1866/PRO4302