MA1-24915 detects Aquaporin 1 from rat samples.
MA1-24915 has been successfully used in ELISA, immunoprecipitation, and Western blot procedures. Predicted moleuclar weight is 32.28 kDa by western blot. Possible positive control for MA1-24915 is kidney tissue.
The MA1-24915 immunogen is a synthetic peptide corresponding to residues 198-208 of rat Aquaporin 1.
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
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Protein Aliases: AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); Aquaporin-1; Aquaporin-CHIP; Water channel protein for red blood cells and kidney proximal tubule
Gene Aliases: Aqp1; CHIP28
UniProt ID: (Rat) Q5EB50
Entrez Gene ID: (Rat) 25240
Molecular Function: transporter