|Tested species reactivity||Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to mouse Argonaute 2|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunoprecipitation (IP)||See 1 publications below|
It is not recommended to aliquot this antibody.
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
miR-21 promotes fibrosis in an acute cardiac allograft transplantation model.
MA5-14861 was used in immunoprecipitation to elucidate miR-21 that induces fibrosis in an acute cardiac allograft transplantation model
|Gupta SK,Itagaki R,Zheng X,Batkai S,Thum S,Ahmad F,Van Aelst LN,Sharma A,Piccoli MT,Weinberger F,Fiedler J,Heuser M,Heymans S,Falk CS,Förster R,Schrepfer S,Thum T||Cardiovascular research (110:215)||2016|