|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues G(127) P G S R A R A A G A R G C(140) of human Artemin.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4142 detects human Artemin.
PA1- 4142 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~20 kDa protein representing human Artemin in dorsal root ganglia/CNS preparation.
The PA1- 4142 immunogen is a synthetic peptide corresponding to residues G(127) P G S R A R A A G A R G C(140) of human Artemin.
Artemin is a novel member of the GDNF family and demonstrated that it is the ligand for the former orphan receptor GFRalpha3-RET. Artemin is a survival factor for sensory and sympathetic neurons in culture, and its expression pattern suggests that it also influences these neurons in vivo. Artemin can also activate the GFRalpha1-RET complex and supports the survival of dopaminergic midbrain neurons in culture
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.