Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product # 7KMWCO
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Protein Aliases: Bcl-2-modifying factor; FLJ00065
Gene Aliases: BMF
UniProt ID: (Human) Q96LC9
Entrez Gene ID: (Human) 90427