This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors.
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Protein Aliases: Butyrate response factor 1; Butyrate response factor 2; early response factor Berg36; EGF-inducible protein CMG1; EGF-response factor 1; EGF-response factor 2; ERF-1; ERF-2; mRNA decay activator protein ZFP36L1; mRNA decay activator protein ZFP36L2; TPA-induced sequence 11b; TPA-induced sequence 11d; ZFP36 ring finger protein-like 1; ZFP36 ring finger protein-like 2; ZFP36-like 1; ZFP36-like 2; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H type-like 2; zinc finger protein 36, C3H type-like 2-like; Zinc finger protein 36, C3H1 type-like 1; Zinc finger protein 36, C3H1 type-like 2; zinc finger protein, C3H type, 36-like 1; zinc finger protein, C3H type, 36-like 2
Gene Aliases: AW742437; AW743212; BERG36; BOS_11072; BOS_11576; BRF1; BRF2; Cmg1; D530020L18Rik; ERF-1; ERF-2; ERF1; ERF2; RNF162B; RNF162C; TIS11B; TIS11D; ZFP36L1; ZFP36L2
Entrez Gene ID: (Human) 677, (Bovine) 614773, (Dog) 490748, (Bovine) 767898, (Human) 678, (Dog) 100856710, (Rat) 29344, (Mouse) 12192, (Guinea pig) 100721072, (Guinea pig) 100724488, (Mouse) 12193, (Rat) 298765