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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the N-terminus of human C/EBP zeta|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 121 kDa.
Purity is >95% by SDS-PAGE.
C/EBP family members include C/EBP alpha, C/EBP beta, C/EBP gamma, C/EBP delta, C/EBP epsilon and C/EBP zeta, all of which are capable of forming homodimers or heterodimers with each other. C/EBP zeta, also known as CBF2, NOC1, CHOP10 (C/EBP homologous protein 10), GADD153 (growth arrest and DNA damage-inducible gene 153) or HSPCBF, is a ubiquitously expressed 1,054 amino acid protein that localizes to the nucleus and regulates transcription. More specifically, C/EBP zeta is believed to play a role regulating the expression of CRP (C-reactive protein). Unlike most C/EBP dimers, C/EBP zeta-containing dimers do not bind the classical C/EBP-binding consensus sequence. Rather, C/EBP zeta-containing dimers must associate with RBP-Jk (another transcription factor) in order to accomplish binding to the C/EBP site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CBF; CBF2; CCAAT binding factor; CCAAT box binding transcription factor; CCAAT-box-binding transcription factor; CCAAT/enhancer binding protein (C/EBP), zeta; CCAAT/enhancer binding protein cebp family zeta; CCAAT/enhancer binding protein zeta; CCAAT/enhancer-binding protein zeta; Cebpz; HSPCBF
CBF; CBF2; CEBPZ; HSP-CBF; NOC1