|ELISA (ELISA)||0.1 µg/ml|
|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Chicken / IgY|
|Immunogen||Full length native protein(Human).|
|Purification||Antigen affinity chromatography|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-20847 detects C Reactive Protein in Human samples.
PA1-20847 has been successfully used in ELISA and Western Blot procedures.
PA1-20847 immunogen corresponds to Full length native protein(Human)..
C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-reactive protein; MGC149895; MGC88244; pentraxin 1; PTX1
Gene Aliases: CRP; PTX1
UniProt ID: (Human) P02741
Entrez Gene ID: (Human) 1401
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.