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Antibody detects endogenous levels of total ASUN.
Crucial regulator of the mitotic cell cycle and development. At prophase, required for dynein anchoring to the nuclear envelope important for proper centrosome-nucleus coupling. At G2/M phase, may be required for proper spindle formation and execution of cytokinesis. Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing (PubMed:23904267). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: asunder spermatogenesis regulator; asunder, spermatogenesis regulator homolog (Drosphila); Cell cycle regulator Mat89Bb homolog; Germ cell tumor 1; Integrator complex subunit 13; likely orthologue of H. sapiens chromosome 12 open reading frame 11 (C12orf11); Protein asunder homolog; Sarcoma antigen NY-SAR-95; spermatogenesis associated 30; Spermatogenesis-associated protein 30
Gene Aliases: 4933424B01Rik; ASUN; C12orf11; GCT1; INTS13; Mat89Bb; NET48; SPATA30
UniProt ID: (Human) Q9NVM5, (Mouse) Q8QZV7
Entrez Gene ID: (Human) 55726, (Rat) 690728, (Mouse) 71177
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