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Product Details
H00000783-M01
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
6C1
Immunogen
CACNB2 (NP_963890, 213 a.a. approximately 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: PSSRKSTPPS SAIDIDATGL DAEENDIPAN HRSPKPSANS VTSPHSKEKR MPFFKKTEHT PPYDVVPSMR PVVLVGPSLK GYEVTDMMQ
Target Information
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAB2; CACNLB1; Calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; Lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; MYSB; Voltage-dependent L-type calcium channel subunit beta-2; voltage-gated calcium channel beta2 subunit transcript variant X13
Gene Aliases: AW060387; CAB2; CACNB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB
UniProt ID: (Human) Q08289, (Mouse) Q8CC27, (Rat) Q8VGC3
Entrez Gene ID: (Human) 783, (Mouse) 12296, (Rat) 116600
voltage-gated calcium channel activity
calcium channel regulator activity
calcium channel activity
protein binding
high voltage-gated calcium channel activity
protein kinase binding
protein domain specific binding
actin filament binding
phosphoprotein binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated ion channel activity
voltage-gated ion channel
chemical synaptic transmission
neuromuscular junction development
visual perception
positive regulation of calcium ion transport
cardiac conduction
calcium ion import
calcium ion transmembrane transport
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
establishment of protein localization to plasma membrane
membrane depolarization during atrial cardiac muscle cell action potential
regulation of voltage-gated calcium channel activity
positive regulation of high voltage-gated calcium channel activity
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
transport
ion transport
calcium ion transport
regulation of ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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