Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CaVGamma8; Neuronal voltage-gated calcium channel gamma-8 subunit; TARP gamma 8; TARP gamma-8; Transmembrane AMPAR regulatory protein gamma-8; Voltage-dependent calcium channel gamma-8 subunit
Gene Aliases: Cacng8; mir-935
UniProt ID: (Rat) Q8VHW5