Product References
Role of Nox4 in Mitigating Inflammation and Fibrosis in Dextran Sulfate Sodium-Induced Colitis.
Cellular and molecular gastroenterology and hepatology
Lee Y,Kim SH,Jeong H,Kim KH,Jeon D,Cho Y,Lee D,Nam KT
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Immunohistochemistry
Tue Aug 22 00:00:00 EDT 2023
Dlk1 maintains adult mice long-term HSCs by activating Notch signaling to restrict mitochondrial metabolism.
Experimental hematology & oncology
Huang D,Han Y,Tang T,Yang L,Jiang P,Qian W,Zhang Z,Qian X,Zeng X,Qian P
48-1271-82 was used in Flow cytometry/Cell sorting to demonstrate that Dlk1 is essential for maintaining HSC homeostasis, which is realized by governing Notch signalling and restricting mitochondrial metabolic activity.
Wed Jan 18 00:00:00 EST 2023
Group 2 Innate Lymphoid Cells Protect Mice from Abdominal Aortic Aneurysm Formation via IL5 and Eosinophils.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Zhang Y,Liu T,Deng Z,Fang W,Zhang X,Zhang S,Wang M,Luo S,Meng Z,Liu J,Sukhova GK,Li D,McKenzie ANJ,Libby P,Shi GP,Guo J
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Wed Mar 01 00:00:00 EST 2023
MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism.
Cancer cell
Ueda K,Kumari R,Schwenger E,Wheat JC,Bohorquez O,Narayanagari SR,Taylor SJ,Carvajal LA,Pradhan K,Bartholdy B,Todorova TI,Goto H,Sun D,Chen J,Shan J,Song Y,Montagna C,Xiong S,Lozano G,Pellagatti A,Boultwood J,Verma A,Steidl U
48-1271-82 was used in Flow cytometry/Cell sorting to identify MDMX overexpression as a pervasive preleukemic-to-AML transition mechanism in different genetically driven disease subtypes, and reveal Wnt/β-Catenin as a non-canonical MDMX-driven pathway with therapeutic potential for progression prevention and cancer interception.
Mon Apr 12 00:00:00 EDT 2021
MicroRNA‑21‑5p protects melanocytes via targeting STAT3 and modulating Treg/Teff balance to alleviate vitiligo.
Molecular medicine reports
Huo J,Liu T,Li F,Song X,Hou X
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Fri Jan 01 00:00:00 EST 2021
PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory.
Cell reports
Cannons JL,Villarino AV,Kapnick SM,Preite S,Shih HY,Gomez-Rodriguez J,Kaul Z,Shibata H,Reilley JM,Huang B,Handon R,McBain IT,Gossa S,Wu T,Su HC,McGavern DB,O'Shea JJ,McGuire PJ,Uzel G,Schwartzberg PL
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Tue Oct 12 00:00:00 EDT 2021
Hedgehog interacting protein-expressing lung fibroblasts suppress lymphocytic inflammation in mice.
JCI insight
Yun JH,Lee C,Liu T,Liu S,Kim EY,Xu S,Curtis JL,Pinello L,Bowler RP,Silverman EK,Hersh CP,Zhou X
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Wed Sep 08 00:00:00 EDT 2021
RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes.
Frontiers in immunology
Rana A,de Almeida FC,Paico Montero HA,Gonzales Carazas MM,Bortoluci KR,Sad S,Amarante-Mendes GP
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Fri Mar 26 00:00:00 EDT 2021
An Id2RFP-Reporter Mouse Redefines Innate Lymphoid Cell Precursor Potentials.
Immunity
Xu W,Cherrier DE,Chea S,Vosshenrich C,Serafini N,Petit M,Liu P,Golub R,Di Santo JP
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Tue Apr 16 00:00:00 EDT 2019
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells.
Nature immunology
Twohig JP,Cardus Figueras A,Andrews R,Wiede F,Cossins BC,Derrac Soria A,Lewis MJ,Townsend MJ,Millrine D,Li J,Hill DG,Uceda Fernandez J,Liu X,Szomolay B,Pepper CJ,Taylor PR,Pitzalis C,Tiganis T,Williams NM,Jones GW,Jones SA
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Mon Apr 01 00:00:00 EDT 2019
Bone marrow adipose tissue-derived stem cell factor mediates metabolic regulation of hematopoiesis.
Haematologica
Zhang Z,Huang Z,Ong B,Sahu C,Zeng H,Ruan HB
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Sun Sep 01 00:00:00 EDT 2019
Single-Cell Profiling Defines Transcriptomic Signatures Specific to Tumor-Reactive versus Virus-Responsive CD4+ T Cells.
Cell reports
Magen A,Nie J,Ciucci T,Tamoutounour S,Zhao Y,Mehta M,Tran B,McGavern DB,Hannenhalli S,Bosselut R
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Tue Dec 03 00:00:00 EST 2019
Inactivation of mTORC1 Signaling in Osterix-Expressing Cells Impairs B-cell Differentiation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Wang Y,Xiao M,Tao C,Chen J,Wang Z,Yang J,Chen Z,Zou Z,Liu A,Cai D,Jiang Y,Ding C,Li M,Bai X
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Sun Apr 01 00:00:00 EDT 2018
The interplay of BMP4 and IL‑7 regulates the apoptosis of intestinal intraepithelial lymphocytes under conditions of ischemia̸reperfusion.
International journal of molecular medicine
Luo B,Chen K,Feng Q,Xiao W,Ma D,Yang H,Zhang C
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Tue May 01 00:00:00 EDT 2018
Oncofetal gene SALL4 reactivation by hepatitis B virus counteracts miR-200c in PD-L1-induced T cell exhaustion.
Nature communications
Sun C,Lan P,Han Q,Huang M,Zhang Z,Xu G,Song J,Wang J,Wei H,Zhang J,Sun R,Zhang C,Tian Z
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Wed Mar 28 00:00:00 EDT 2018
Direct conversion of injury-site myeloid cells to fibroblast-like cells of granulation tissue.
Nature communications
Sinha M,Sen CK,Singh K,Das A,Ghatak S,Rhea B,Blackstone B,Powell HM,Khanna S,Roy S
48-1271 was used in Flow cytometry/Cell sorting to introduce a paradigm wherein myeloid cells are recognized as a major source of fibroblast-like cells in granulation tissue.
Mon Mar 05 00:00:00 EST 2018
Combined blockade of the IL-13 and IL-33 pathways leads to a greater inhibition of type 2 inflammation over inhibition of either pathway alone.
The Journal of allergy and clinical immunology
Ramirez-Carrozzi V,Sambandam A,Zhou M,Yan D,Kang J,Wu X,Suto E,Baca M,Austin C,Xu M,Lee W,Pappu R
48127182 was used in flow cytometry to study the effect of IL-13 and IL-33 pathways in dysregulated type 2 inflammation.
Wed Feb 01 00:00:00 EST 2017
IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model.
PLoS medicine
Xu J,Guardado J,Hoffman R,Xu H,Namas R,Vodovotz Y,Xu L,Ramadan M,Brown J,Turnquist HR,Billiar TR
48-1271 was used in Flow cytometry/Cell sorting to suggest that IL33 may initiate early detrimental type 2 immune responses after trauma through ILC2 regulation of neutrophil IL5 production.
Sat Jul 01 00:00:00 EDT 2017
PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Biology open
Carofino BL,Ayanga B,Tracey LJ,Brooke-Bisschop T,Justice MJ
48-1271 was used in Flow cytometry/Cell sorting to investigate how PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.
Sun May 15 00:00:00 EDT 2016
A simple, accurate and universal method for quantification of PCR.
BMC biotechnology
Boulter N,Suarez FG,Schibeci S,Sunderland T,Tolhurst O,Hunter T,Hodge G,Handelsman D,Simanainen U,Hendriks E,Duggan K
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Wed Mar 09 00:00:00 EST 2016
Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis.
PloS one
Arcipowski KM,Bulic M,Gurbuxani S,Licht JD
48-1271 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which MLL3 loss contributes to myeloid malignancies, showing that it promotes aberrant myelopoiesis.
Mon Aug 28 00:00:00 EDT 2017
Production of IL-10 by CD4(+) regulatory T cells during the resolution of infection promotes the maturation of memory CD8(+) T cells.
Nature immunology
Laidlaw BJ,Cui W,Amezquita RA,Gray SM,Guan T,Lu Y,Kobayashi Y,Flavell RA,Kleinstein SH,Craft J,Kaech SM
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2015
WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.
The Journal of experimental medicine
Xia P,Wang S,Huang G,Zhu P,Li M,Ye B,Du Y,Fan Z
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Mon Sep 22 00:00:00 EDT 2014
Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses.
Molecular therapy : the journal of the American Society of Gene Therapy
Ip PP,Boerma A,Regts J,Meijerhof T,Wilschut J,Nijman HW,Daemen T
48-1271 was used in Flow cytometry/Cell sorting to study an rSFV-based vector which induces robust T-cell activity and has a potential for the treatment of HCV infections.
Tue Apr 01 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
48-1271 was used in Flow cytometry/Cell sorting to assess the effect of eosinophils on B cell survival, proliferation, and Ig secretion.
Tue Apr 15 00:00:00 EDT 2014
Autophagy is a critical regulator of memory CD8(+) T cell formation.
eLife
Puleston DJ,Zhang H,Powell TJ,Lipina E,Sims S,Panse I,Watson AS,Cerundolo V,Townsend AR,Klenerman P,Simon AK
48-1271 was used in Flow cytometry/Cell sorting to show that mice lacking the autophagy gene Atg7 in T cells failed to establish CD8(+) T cell memory to influenza and MCMV infection.
Tue Nov 11 00:00:00 EST 2014
A mouse model for inducible overexpression of Prdm14 results in rapid-onset and highly penetrant T-cell acute lymphoblastic leukemia (T-ALL).
Disease models & mechanisms
Carofino BL,Ayanga B,Justice MJ
48-1271 was used in Flow cytometry/Cell sorting to demonstrate that increased expression of Prdm14 drives development of T-Cell acute lymphoblastic leukemia in mice.
Fri Nov 01 00:00:00 EDT 2013
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950)
Singh K,Gatzka M,Peters T,Borkner L,Hainzl A,Wang H,Sindrilaru A,Scharffetter-Kochanek K
48-1271 was used in Flow cytometry/Cell sorting to investigate the influence of adhesion molecules on the differentiation of Foxp3(+) Tregs into proinflammatory Th17 cells occurring in lesional skin and blood of psoriasis patients.
Fri Mar 15 00:00:00 EDT 2013
A self-reinforcing regulatory network triggered by limiting IL-7 activates pre-BCR signaling and differentiation.
Nature immunology
Ochiai K,Maienschein-Cline M,Mandal M,Triggs JR,Bertolino E,Sciammas R,Dinner AR,Clark MR,Singh H
Published figure using CD127 monoclonal antibody (Product # 48-1271-82) in Flow Cytometry
Sun Jan 22 00:00:00 EST 2012
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus.
Nature immunology
Monticelli LA,Sonnenberg GF,Abt MC,Alenghat T,Ziegler CG,Doering TA,Angelosanto JM,Laidlaw BJ,Yang CY,Sathaliyawala T,Kubota M,Turner D,Diamond JM,Goldrath AW,Farber DL,Collman RG,Wherry EJ,Artis D
48-1271 was used in Flow cytometry/Cell sorting to demonstrate a critical role for lung ILCs in restoring airway epithelial integrity and tissue homeostasis after viral replication.
Tue Nov 01 00:00:00 EDT 2011
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.
Journal of immunology (Baltimore, Md. : 1950)
Vondenhoff MF,Greuter M,Goverse G,Elewaut D,Dewint P,Ware CF,Hoorweg K,Kraal G,Mebius RE
Fri May 01 00:00:00 EDT 2009
Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis.
The American journal of pathology
Leithäuser F,Meinhardt-Krajina T,Fink K,Wotschke B,Möller P,Reimann J
Thu Jun 01 00:00:00 EDT 2006