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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-23611 detects CD14 Monocyte in Human samples.
MA1-23611 has been successfully used in Immunofluorescence procedures.
MA1-23611 immunogen corresponds to Monocytes (Human).
CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS)-dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram-negative shock.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cell-surface MMP-9 regulates the invasive capacity of leukemia blast cells with monocytic features.
MA1-23611 was used in flow cytometry to study the role of cell surface MMP-9 in regulating the invasive capacity of leukemia blast cells
|Paupert J,Mansat-De Mas V,Demur C,Salles B,Muller C||Cell cycle (Georgetown, Tex.) (7:1047)||2008|
Immortalization of human urethral epithelial cells: a model for the study of the pathogenesis of and the inflammatory cytokine response to Neisseria gonorrhoeae infection.
MA1-23611 was used in immunocytochemistry to develop an immortalized human urethral epithelial cell line to study the pathogenesis Neisseria gonorrhoeae infection
|Harvey HA,Post DM,Apicella MA||Infection and immunity (70:5808)||2002|
monocyte differentiation antigen CD14; myeloid cell-specific leucine-rich glycoprotein