Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Fc ALCAM consists of the Fc part of human immunoglobin and the extracellular part of ALCAM. This antibody is positive on K526 cells transfected with C-DNA encoding ALCAM and is negative on K526 cells. It blocks ALCAM-ALCAM interations and is reactive with the C-type domains. The antibody recognizes an epitope in two domains close to the membrane.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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