|Immunohistochemistry (Paraffin) (IHC (P))||3-6 µg/ml|
|Western Blot (WB)||0.3-1 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (PDALEEPDDQNRI) corresponding to the C-terminus amino acids of FCGR2B|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus . Several transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD32; CD32 receptor 2b; CDw32; Fc fragment of IgG; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc gamma Receptor II-b; Fc gamma receptor IIb; Fc gamma RIIb; Fc-gamma RII-b; Fc-gamma RII-c; Fc-gamma-RIIb; Fc-gamma-RIIc; FCG2; FCGR2; fcRII-b; FGFR2B; IGFR2; IgG Fc receptor II-b; IgG Fc receptor II-c; low affinity II; Low affinity immunoglobulin gamma Fc region receptor II-b; Low affinity immunoglobulin gamma Fc region receptor II-c; receptor for CD32
Gene Aliases: CD32; CD32B; FCG2; FCGR2; FCGR2B; FCGR2C; IGFR2
UniProt ID: (Human) P31994
Entrez Gene ID: (Human) 2213
Molecular Function: cell adhesion molecule
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