|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Fusion protein corresponding to the variable domains (v3 to v10) of human CD44.|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50-1:200|
|Immunohistochemistry (Frozen) (IHC (F))||1:400-1:500|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Expression of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma.
MA1-82392 was used in immunohistochemistry to investigate the expression and the prognostic significance of the membrane-cytoskeletal linker Ezrin in salivary gland adenoid cystic carcinoma
|Wang YY,Chen WL,Huang ZQ,Yang ZH,Zhang B,Wang JG,Li HG,Li JS||Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics (112:96)||2011|
Role of p53, CD44V6 and CD57 in differentiating between benign and malignant follicular neoplasms of the thyroid.
MA1-82392 was used in immunohistochemistry - paraffin section to determine the role of immunohistochemical markers in the differential diagnosis of follicular lesions of the thyroid
|Nasir A,Catalano E,Calafati S,Cantor A,Kaiser HE,Coppola D||In vivo (Athens, Greece) (18:189)||2004|
Cd44: a marker of squamous differentiation in adenosquamous neoplasms.
MA1-82392 was used in immunohistochemistry (paraffin) to test if CD44, CD44v6, and CD44v7-8 are useful markers of squamous differentiation in epithelial tumors.
|Ylagan LR,Scholes J,Demopoulos R||Archives of pathology and laboratory medicine (124:212)||2000|