|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Stimulated human leucocytes.|
|Storage buffer||PBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control is tonsil tissue.
CD45 or Leukocyte Common Antigen (LCA/T200) is a membrane sialoglycoproteins with three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates various isoforms. CD45RA.is a single chain glycoprotein. It is expressed on appoximately 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. CD45RA are naive or virgin T-cells while, T-cells expressing CD45RO are memory T-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.