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|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Mouse B cell Lymphoma, 38C-14|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/1 million cells|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-70074 detects CD62L in mouse samples.
MA1-70074 has been successfully used in flow cytometry, immunohistochemistry and immunoprecipitation procedures.
The MA1-70074 immunogen is mouse B cell Lymphoma, 38C-14.
The human CD62L is a 74-95 kD glycoprotein member of the selectin family of adhesion receptors. L-Selectin is comprised of an aminoterminal C-type lectin binding domain, an epidermal growth factor-like domain, two short consensus repeat (SCR) sequences homologous to those found in complement binding proteins, a short spacer region, a transmembrane region and a short cytoplasmic region. Human CD62L (L-Selectin) is constitutively expressed on all classes of leukocytes including lymphocytes (except a substantial population of memory T cells), monocytes and polymorphonuclear cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Retinoic acid enhances the T helper 2 cell development that is essential for robust antibody responses through its action on antigen-presenting cells.
MA1-70074 was used in flow cytometry to investigate how all-trans retinoic acid enhances Th2 development.
|Hoag KA,Nashold FE,Goverman J,Hayes CE||The Journal of nutrition (132:3736)||2002|
Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4.
MA1-70074 was used in flow cytometry to identify the initial source of IL-4 in early immune responses.
|Liu L,Rich BE,Inobe J,Chen W,Weiner HL||International immunology (10:1017)||1998|
CD62 antigen-like family member L; hLHRc; L-selectin; LAM-1; LAM1; LECAM1; Leu-8; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; Lyam-1; LYAM1; lymph node homing receptor; lymphocyte antigen 22; lymphocyte surface MEL-14 antigen; PLNHR; SELL
AI528707; CD62L; L-selectin; LECAM-1; Lnhr; Ly-22; Ly-m22; Ly22; Lyam-1; Lyam1; Sell