Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: YLVPGMTYSK GKIYPVGYFT KENPVKGSPG VPSFAAGPPI SEGKYFSSNP
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
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Protein Aliases: Corneodesmosin; D6S586E; differentiated keratinocyte S protein; S protein
Gene Aliases: CDSN; HTSS; HTSS1; HYPT2; PSS; PSS1; S
UniProt ID: (Human) B0S7V2
Entrez Gene ID: (Human) 1041
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