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This antibody is predicted to react with rat based on sequence homology.
The casein kinase I (CKI) gene family encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric and range from 25 to 55 kD. They are ubiquitous, being found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells. In eukaryotic cells, CKI is in volved in regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
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