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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human CLOCK expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15625 targets CLOCK in IF and WB applications and shows reactivity with Human samples.
The MA5-15625 immunogen is purified recombinant fragment of human CLOCK expressed in E. Coli.
MA5-15625 detects CLOCK which has a predicted molecular weight of approximately 95kDa.
This gene encodes a protein that belongs to the basic helix-loop-helix family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
bHLHe8; circadian locomoter output cycles kaput protein; class E basic helix-loop-helix protein 8; CLOCK; clock homolog; KAT13D; KIAA0334
BHLHE8; CLOCK; KAT13D; KIAA0334