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|Tested species reactivity||Human, Mouse, Non-human primate, Rat|
|Published species reactivity||Bovine|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human COX4I1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1/200 - 1/400|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
MA5-15686 targets COX4I1 in FACS, IF, and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples.
The MA5-15686 immunogen is purified recombinant fragment of human COX4I1 expressed in E. Coli.
MA5-15686 detects COX4I1 which has a predicted molecular weight of approximately 19kDa.
Cytochrome c oxidase is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 gene in a head-to-head orientation, and shares a promoter with it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Cartilage tissue formation using redifferentiated passaged chondrocytes in vitro.
MA5-15686 was used in immunohistochemistry to study cartilage tissue formation using re-differentiated passaged chondrocytes in vitro
|Ahmed N,Gan L,Nagy A,Zheng J,Wang C,Kandel RA||Tissue engineering. Part A (15:665)||2009|
COX IV-1; COX4; COX4-1; COX4I1; COXIV; cytochrome c oxidase polypeptide IV; cytochrome c oxidase subunit 4 isoform 1, mitochondrial; cytochrome c oxidase subunit IV; cytochrome c oxidase, subunit 4a; cytochrome c oxidase, subunit IV; cytochrome c oxidase, subunit IVa; MGC72016
AL024441; COX; COX IV-1; COX4; COX4-1; Cox4a; COX4I1; COXIV; COXIV-1; IV-1