|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 256 of Human CSEN|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28330 targets CSEN in WB applications and shows reactivity with Human and mouse samples.
The PA5-28330 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 256 of Human CSEN.
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A-type potassium channel modulatory protein 3; Calsenilin; calsenilin, presenilin binding protein, EF hand transcription factor; calsenilin, presenilin-binding protein, EF hand transcription factor; CSEN; DRE-antagonist modulator; DREAM; EF hand transcription factor; KCHIP3; Kv channel interacting protein 3; Kv channel interacting protein 3, calsenilin; Kv channel-interacting protein 3; potassium channel interacting protein 3; presenilin-binding protein
Gene Aliases: 4933407H12Rik; AI413860; CSEN; DREAM; KCHIP3; KCNIP3; R74849
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