Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Chimpanzee (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adapt78; Calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; MCIP1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Regulator of calcineurin 1
Gene Aliases: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCAN1; RCN1
UniProt ID: (Human) P53805
Entrez Gene ID: (Human) 1827
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