|Tested species reactivity||Dog, Horse, Human, Mouse, Non-human primate, Sheep, Pig, Rat|
|Published species reactivity||Rat, Human, Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic human calcitonin 1-32 amino acid peptide|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-14552 targets Calcitonin in IHC (P) applications and shows reactivity with Canine, Equine, Human, mouse, Non-human primate, Ovine, Porcine, and Rat samples.
The MA5-14552 immunogen is synthetic human calcitonin 1-32 amino acid peptide.
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thyroid Paraganglioma Diagnosed by Fine-Needle Aspiration Biopsy, Correlated With Histopathological Findings: Report of a Case.
MA5-14552 was used in immunohistochemistry to characterize a case where diagnosis of thyroid paraganglioma occurred by fine-needle aspiration biopsy and histopathological findings
|Çetin ¿,Kir G,Yilmaz M||Diagnostic cytopathology (44:643)||2016|
Calcitonin is expressed in the submaxillary glands of rats.
MA5-14552 was used in immunocytochemistry and immunohistochemistry to study the rat submaxillary gland expression of calcitonin
|Zhang Y,Li B,Fu Z,Li S||Bosnian journal of basic medical sciences (14:35)||2014|
Absence of gene mutations in KIT-positive carcinoma showing thymus-like elements of the thyroid.
MA5-14552 was used in immunohistochemistry to study whether KIT mutations are involved in carcinoma showing thymus-like elements of the thyroid
|Pan Y,Zhao X,Yang J,Deng J,Zhan Z,Luo Y,Li Q,Guo Y,Zhai Q,Sun B||Human pathology (43:350)||2012|
Liquid-based cytologic findings of solitary extramedullary plasmacytoma in thyroid: a case report identified with fine-needle aspiration cytology.
MA5-14552 was used in immunocytochemistry to report on a case of solitary extramedullary plasmacytoma of the thyroid
|Lee CH,Jung YY,Chung YR,Ryu HS||Diagnostic cytopathology (42:964)||2014|