Recommended positive controls: Thyroid or Medullary carcinoma.
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin-related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; CCP; CGRP-I; Katacalcin; PDN-21
Gene Aliases: CALC1; CALCA; CGRP; CGRP-I; CGRP1; CT; KC; PCT
UniProt ID: (Human) P06881
Entrez Gene ID: (Human) 796
Molecular Function: peptide hormone