Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
MA1-26935 detects cardiac Troponin T from human samples.
MA1-26935 has been successfully used in ELISA, immunohistochemistry (frozen), immunohistochemistry (paraffin), immunoprecipitation, and Western blot procedures.
The MA1-26935 immunogen is highly purified human cardiac troponin T.
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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