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|Tested species reactivity||Mouse, Rat|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Recombinant p30 subunit of mouse caspase 11.|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||5-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-24703 detects Caspase 11 from mouse samples. MA1-24703 is expected to cross react with rat due to sequence homology.
MA1-24703 has been successfully used in IHC (Fr), immunoprecipitation, and Western blot procedures.
The MA1-24703 immunogen is recombinant p30 subunit of mouse caspase 11.
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Casp11; caspase 11; caspase 4; Caspl; ich-3
CASP-11; CASP-4; Casp11; Casp4; Caspl; ich-3; Ich3