|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues D(171) L A N R F K E F G K K M V K L(186) of human alpha 2-Catenin.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20251 detects alpha-2 Catenin in human samples.
PA1-20251 has been successfully used in Western blot procedures.
The PA1-20251 is a synthetic peptide corresponding to residues D(171) L A N R F K E F G K K M V K L(186) of human alpha 2-Catenin.
The catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.