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In direct ELISAs, approximately 35% cross-reactivity with recombinant mouse Cathepsin X/Z/P is observed and less than 5% cross-reactivity with recombinant human Cathepsin C is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: carboxypeptidase LB; cathepsin B2; cathepsin IV; Cathepsin P; Cathepsin X; Cathepsin Y; Cathepsin Z; cathepsin Z1; cysteine-type carboxypeptidase; lysosomal carboxypeptidase B; preprocathepsin P
Gene Aliases: AI787083; AU019819; CATX; CTSX; Ctsy; CTSZ; D2Wsu143e
UniProt ID: (Human) Q9UBR2, (Mouse) Q9WUU7, (Rat) Q9R1T3
Entrez Gene ID: (Human) 1522, (Mouse) 64138, (Rat) 252929
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