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MA5-17553 targets Crry in FACS and IHC (F) applications and shows reactivity with Rat samples.
The MA5-17553 immunogen is erythrocytes from a C3 mutated rat.
This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Protein Aliases: 5I2 antigen; Antigen 5I2; Complement component receptor 1-like protein; Complement receptor related protein; complement receptor type 1; Complement regulatory protein Crry; MGC129536
Gene Aliases: Cr1; Cr1l; Crry
UniProt ID: (Rat) Q63135
Entrez Gene ID: (Rat) 54243
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