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|Tested species reactivity||Human|
|Published species reactivity||Sheep, Mouse, Human|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15.|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:25-1:50|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-90926 detects Cytokeratin 15 from human samples.
MA1-90926 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue) applications.
The MA1-90926 immunogen is: A 17-mer synthetic peptide from the C-terminus of human cytokeratin 15.
Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperprol
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A functional role of RB-dependent pathway in the control of quiescence in adult epidermal stem cells revealed by genomic profiling.
MA1-90926 was used in immunohistochemistry to investigate the mechanism for the regulation of hair follicle stem cell homeostasis
|Lorz C,García-Escudero R,Segrelles C,Garín MI,Ariza JM,Santos M,Ruiz S,Lara MF,Martínez-Cruz AB,Costa C,Buitrago-Pérez A,Saiz-Ladera C,Dueñas M,Paramio JM||Stem cell reviews (6:162)||2010|
Expression of the embryonic stem cell transcription factor SOX2 in human skin: relevance to melanocyte and merkel cell biology.
MA1-90926 was used in immunohistochemistry to study the role of embryonic stem cell transcription factor SOX2 in malonogenesis and Merkel cell ontogeny
|Laga AC,Lai CY,Zhan Q,Huang SJ,Velazquez EF,Yang Q,Hsu MY,Murphy GF||The American journal of pathology (176:903)||2010|
Multipotent hair follicle stem cells promote repair of spinal cord injury and recovery of walking function.
MA1-90926 was used in immunohistochemistry to examine the application of hair follicle stem cells in spinal cord injury repair and recovery
|Amoh Y,Li L,Katsuoka K,Hoffman RM||Cell cycle (Georgetown, Tex.) (7:1865)||2008|
Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves.
MA1-90926 was used in immunohistochemistry to investigate the transdifferentiation ability of hair follicle stem cells
|Amoh Y,Li L,Campillo R,Kawahara K,Katsuoka K,Penman S,Hoffman RM||Proceedings of the National Academy of Sciences of the United States of America (102:17734)||2005|
Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons.
MA1-90926 was used in immunohistochemistry to study the differentiation of hair-follicle bulge stem cells
|Amoh Y,Li L,Katsuoka K,Penman S,Hoffman RM||Proceedings of the National Academy of Sciences of the United States of America (102:5530)||2005|
An improved method of human keratinocyte culture from skin explants: cell expansion is linked to markers of activated progenitor cells.
MA1-90926 was used in immunocytochemistry to investigate the effectivenss of a novel method for human keratinocyte preparation
|Guo A,Jahoda CA||Experimental dermatology (18:720)||2009|
Isolation and identification of stem cells from adult cashmere goat skin.
MA1-90926 was used in immunocytochemistry to examine the totipotency of adult cashmere goat skin epithelia
|Liu Y,Zhou H,Gao F||International journal of dermatology (47:551)||2008|
CK-15; CK15; cytokeratin 15; Cytokeratin-15; K15; K1CO; keratin 15, type I; Keratin, type I cytoskeletal 15; Keratin-15; keratin-15, basic; keratin-15, beta; type I cytoskeletal 15
CK15; K15; K1CO; KRT15; KRTB