|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Isolated cytokeratin 5|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10|
|Western Blot (WB)||1:250|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-12429 targets Cytokeratin 5/6 in IHC (P) applications and shows reactivity with Human samples.
The MA5-12429 immunogen is isolated cytokeratin 5.
Twenty human keratins are divided into acidic (pI <5.7) and basic (pI >6.0) subfamilies. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor identification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The clinicopathological and prognostic significance of CD24, CD44, CD133, ALDH1 expressions in invasive ductal carcinoma of the breast: CD44/CD24 expression in breast cancer.
MA5-12429 was used in immunohistochemistry to evaluate the expression of CD24, CD44, CD133 and ALDH1 in invasive ductal carcinoma of the breast
|Kapucuo¿lu N,Bozkurt KK,Ba¿p¿nar ¿,Koçer M,Ero¿lu HE,Akdeniz R,Akçil M||Pathology, research and practice (211:740)||2015|
Receptor tyrosine kinase and downstream signalling analysis in diffuse malignant peritoneal mesothelioma.
MA5-12429 was used in immunohistochemistry to determine the activation profile of EGFR, PDGFRB, and PDGFRA receptors and their downstream effectors in diffuse malignant peritoneal mesothelioma specimens
|Perrone F,Jocollè G,Pennati M,Deraco M,Baratti D,Brich S,Orsenigo M,Tarantino E,De Marco C,Bertan C,Cabras A,Bertulli R,Pierotti MA,Zaffaroni N,Pilotti S||European journal of cancer (Oxford, England : 1990) (46:2837)||2010|