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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (CGEDHPQQGSTLY) corresponding to the internal amino acids of NR0B1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-1.5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
AHC; AHCH; AHX; DAX-1; DAX1; dosage-sensitive sex reversal; DSS; DSS-AHC critical region on the X chromosome protein 1; gonadotropin deficiency; GTD; HHG; NR0B1; NROB1; nuclear hormone receptor; nuclear receptor DAX-1; nuclear receptor subfamily 0, group B, member 1
AHC; AHCH; AHX; DAX-1; DAX1; DSS; GTD; HHG; NR0B1; NROB1; SRXY2